The global stilbene market is seeking to account for remunerative growth over the coming years, with the magnificent growth of textile and paints industry. How would these industries contribute to escalating the growth curve of the stilbene market is that the aforementioned sectors are hugely dependent on dyes, and stilbene is an integral compound found in dye production.

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Stilbene derivatives are deemed to boast of low molecular weight and are being largely used as effective and good brightening agents owing to their superior thermal and chemical resistance which offers a long fluorescence effect. Apart from the textile, paint, and paper industry, the product is also used for production of scintillator in combination with polymers.

Stilbene and its use in scintillators

It has been reported that the use of scintillators is being widely felt across the nuclear industry. Their utility is sufficed by measuring and detecting radioactive contamination and monitoring nuclear materials. Scintillators produce light in fluorescent tubes, to convert the UV of the discharge into visible light. This fluorescence in scintillators is offered by stilbene. 

According to a project report of 2018, stilbene crystal detectors are known to offer a promising approach for nuclear material assay application mainly due to their intrinsic benefits compared to other detectors. The compound is an optimal scintillator detector as it poses high organic scintillation efficacy with a much higher light yield than liquids or plastics. Besides, it also has superior pulse-shape discrimination which enables exceptional neutron and gamma-ray discrimination FOM, leading to high neutron-counting detection efficiency.

An essential thing to note here, regarding the use of stilbene in scintillators. is that, unlike liquid scintillators, stilbene crystals are inflammable or not a combustible hazard, thus simplifying detector shipment and facility acceptance.

Will stilbene derivatives emerge as an inherent compound in pharmaceuticals?

It is surprising to note that stilbene derivatives are expected to emerge as pivotal compounds for treating innumerable medical ailments and conditions. One of the major applications of the product here is the use in alleviating the conditions of fungal infections, thus acting as an antifungal compound.

Consider the given estimates:

• Fungal diseases had in 2017 incurred $7.2 billion in direct medical costs.
• Fungal infections result in nearly 11.5 million life-threatening infections and over more than 1.5 million fatalities every year.

Although there have been major advancements being made in fungal treatment and antifungal drug development over the past few years, most of the world’s population has not yet been benefited from these. However, the introduction of stilbene derivatives in antifungal treatment is expected to offer new prospects for infection treatment owing to their natural properties. Stilbenes produced by several plants may come out to be useful lead structure for the chemical synthesis of antifungal. Their antifungal potential signifies a useful solution to the drug resistance and side effects that might occur post pharmacological treatment of the diseases.

One of the stilbene derivatives, resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a phytoalexin produced by plant species in response to environmental stress or pathogenic attacks. This stilbene derivative is a natural antifungal agent capable of mediating more intense responses in a more particular way. This can be ascribed to the compound’s potential therapeutic applications in human general homeostasis.

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Apart from antifungal use, stilbene derivatives have also found major applications in the treatment of cancer. According to reliable reports, new synthetic stilbene derivatives demonstrate good bioavailability and significant activity against a large number of cancer cells lines.

With stilbene boasting an extensive array of applications across myriad industries, the market progression is set to account for a billion-dollar business over the span of 2020-2026.

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